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These metrics are especially important given the increased cardiac risks associated with hormonal transitions
Blood 112(11):1011, 2008
Co-formulation strategies - such as GLP-1/GIP dual agonists and GLP-1/insulin combinations - are advancing clinical efficacy in patients with uncontrolled glycemic profiles or obesity-related complications
(Lausanne) 10, 1015711
Current human safety data obtained under approved therapeutic regimens are characterized predominantly by mild-to-moderate gastrointestinal adverse events rather than generalized cytotoxic toxicity, underscoring the need to distinguish preclinical pro-apoptotic observations from clinically established safety profiles
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