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All methods were carried out in accordance with concerned laws and Biosafety Manual in RIKEN

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and after applying the inclusion and exclusion criteria (figure 1), 30 of these were rejected because they did not adjust to the topic of our review, 3 of them were reviews, comments, or other document types, and therefore did not meet the inclusion criteria, and another 2 because the study population were not PTNBs (exclusion criteria)

The recommended daily intake is 1 capsule per day with plenty of water