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Experiments were conducted using DIO male C57BL/6J mice (Janvier Labs) kept on a HFHS diet (58 kcal% fat, D12331i, Research Diets) from 8 weeks of age

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This innovative treatment synergistically combines a fully human monoclonal antibody, aimed at the GIP receptor (GIPR) a target for blood sugar control with a GLP-1 agonist peptide analog , which is a molecule designed to stimulate insulin release [Vniant, M.M

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