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[DOI] [PubMed] [Google Scholar] 153.Hampel H, Mesulam M-M, Cuello AC, Khachaturian AS, Vergallo A, Farlow M

Aim for 64-90 ounces daily (approximately 8-11 cups)

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GLP-1 receptor agonists stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, suppress glucagon release, slow gastric emptying, and act on central nervous system pathways to reduce appetite and food intake

FOXO4-DRI and related constructs have been studied as tools to better understand these mechanisms, potentially offering models to examine how FOXO-related signaling interacts with neurodegenerative processes