-MSH exerts an anti-hypertrophic effect in cultured cardiomyocytes To investigate whether functional MC-Rs exist in cardiomyocytes, we performed experiments with H9c2 cells and neonatal mouse ventricular cardiac myocytes (NMCMs)
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seek urgent medical advice for right upper quadrant pain or jaundice Diabetic retinopathy complications : Patients with pre-existing retinopathy should have regular ophthalmological monitoring, as rapid glycaemic improvement may temporarily worsen retinal disease Renal impairment : Dehydration from gastrointestinal side effects can affect kidney function, particularly in vulnerable patients Injection site reactions (redness, itching, bruising) are common but usually mild
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Interaction Neuronal cells, myoblast, T cells, B cells, NK cells Ligand/Receptor IGF-I receptor, Insulin receptor isoform A, and IGF-II receptor (M-6-P-R) Bioactivity Human LR3 IGF-1 induces the proliferation of MCF-7 human epithelial cells