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Furthermore, inflammation in the gut has been linked to an increase in circulating pro-inflammatory cytokines, which are known to contribute to kidney damage and fibrosis (Lau et al., 2015)

Funding This work was supported by the Sichuan Provincial Central Government-Guided Local Science and Technology Development Project (2024ZYD0120)

Lifestyle modification remains fundamental, and patients should be encouraged to maintain healthy eating patterns, regular physical activity, and adequate hydration (individualised to their clinical situation, particularly for those with heart failure or kidney disease)

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Wang X, Xu W, Zhou H, Zhang Y, Gao W, Zhang W, et al