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Oxidative stress from pollution, smoking, and chronic inflammation can also stimulate melanin production by activating tyrosinase

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The following mutants were generated: for p97-ND1LP246T, P247A, P247K, K251A, D304N, E305Q, K312A, K312E, K312R, K312R-R313A, R313A, R313A-E314R, K315A, N348Q, R349A, R359A, R359A-R362A, R359K, F360A, Cys-F360C-A413C (Cys: C69V-C77V-C105A-C174A-C184W-C209V-C415A), F360P and R362A

J Spinal Cord Med 21:309334 Kaluzna-Czaplinska J, Michalska M, Rynkowski J (2011) Homocysteine level in urine of autistic and healthy children

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