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Certain conditions can make GLP-1 treatment unsuitable - including a personal or family history of medullary thyroid carcinoma, pancreatitis, or multiple endocrine neoplasia type 2

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The drug label also advises against drinking alcohol while taking phentermine and says it may impair the ability to drive or operate machinery

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Tayran H, Yilmaz E, Bhattarai P et al (2024a) ABCA7dependent neuropeptideY signalling is a resilience mechanism required for synaptic integrity in Alzheimers disease