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Alternate names -L-Glutathione, Glutinal, Deltathione, Neuthion, Copren, Glutide

For superoxide anion, the main ROS, a first line of defense is represented by the enzyme superoxide dismutase, localized in the mitochondrial matrix

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however, the GSH antioxidant system can be overwhelmed if ROS are produced in excess, leading to increased levels of free radicals that can damage molecules that are essential to cellular homeostasis and metabolism

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