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Evidence based on recent studies Initially, cases of intestinal obstruction associated with GLP-1 RAs were reported by the European Medicines Agency (EMA) in 2013 [9], and this safety signal is currently being monitored by the United States (US) FDA

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Open Heart 3 (1), e000369

West Virginia and North Carolina Similar to Colorado, West Virginia and North Carolina have encountered similar cost challenges leading them to roll back their own coverage of GLP-1s for weight loss purposes from their state employee health plans