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As VTA is a heterogenous area, different sub-parts thereof may modulate alcohol-mediated behaviors differently

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Those on Certain Medications : Some medications, such as metformin (for diabetes) or proton pump inhibitors (for acid reflux), can interfere with B12 absorption

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Nutrition: Emphasize mitochondrial cofactors including Bvitamins, CoQ10, magnesium, and alphalipoic acid