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Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle

It has not been approved by the FDA for any therapeutic or diagnostic applications

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The peptides under investigation, include: Nle-AngIV (Nle-Tyr-Ile-His-Pro-Phe) and its analogs such as D-Nle-YIH, acetyl-NleYIH, -amino butyric acid-YIH, NleYI-amide, and the primary focus, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide (Dihexa)