Journal of Functional Foods , 22, 327334
NICE guidance (NG100) recommends disease-modifying antirheumatic drugs (DMARDs) as standard care, with methotrexate as first-line therapy
The cardiovascular benefit appears to be partially independent of the weight loss itself, suggesting direct vascular and anti-inflammatory mechanisms beyond caloric reduction
[DOI] [PubMed] [Google Scholar] 110.Lien F., Berthier A., Bouchaert E., Gheeraert C., Alexandre J., Porez G., Prawitt J., Dehondt H., Ploton M., Colin S., et al
Others reported temperature-related complaints, such as chills, feeling cold, hot flashes and fever-like symptoms In addition, fatigue ranked as the second most common complaint among Reddit users, despite reaching reporting thresholds in relatively few clinical trials