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Using the PI(4,5)P-binding ASAP1 Pleckstrin Homology (PH) domain as a model, we show that both conventional mPRE and a new dynamic-exchange mPRE (EX-mPRE) method reproduce the membrane orientation obtained by NR

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J Gen Physiol 154:e202213146 Norton RS, Chandy KG (2017) Venom-derived peptide inhibitors of voltage-gated potassium channels