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Another study investigates the protective effects of polydatin on DED model

Science 287 : 22622267

Paper: Gonzalez-Rellan MJ, Riobello C, Fang S, Martins da Silva E, Koehler JA, Shang R, Hammoud R, Cao X, Varela-Rey M, Drucker DJ

549 Phase I studies showed that a single subcutaneous dose of zilebesiran of 200 mg or more considerably decreased serum AGT levels and 24 h ambulatory blood pressure for up to 24 weeks, with only mild injection site reactions observed