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M1 microglia promote the production and release of pro-inflammatory cytokines, exacerbating nerve damage, while M2 microglia promote the release of repairing and phagocytic neurotrophic factors to maintain immune system balance

The machinery encoded by Rickettsia to import, transfer, or degrade GSH has not been well described

These changes likely contribute to easier sleep initiation, deeper delta-dominant sleep, and adaptogenic/stress-protective effects without strong sedation

Of the three amino acids required to make glutathione (cysteine, glycine and glutamic acid), only cysteine contains sulfur

(University of South Florida) C-peptide has the potential to be a validated endpoint for DMT clinical trials, and researchers like Dr