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The antimicrobial activity of most of the defensins was reduced at increasing salt concentrations or in the presence of bivalent cations [131]

FDA (2023)

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The mechanism is now partly unsupported: Retractions have undermined some of the primary HGF/c-Met synaptogenesis data [4] , and the surviving oral-activity characterization paper carries a 2021 Notice of Concern [2]

Furthermore, iron overload might also be involved in the disturbance of lipid metabolism in NAFLD [132, 133]