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Genetically altered mice to evaluate glutathione homeostasis in health and disease

In radiosensitive HCT116 cells, the addition of metformin to 1.8 Gy X-ray radiation significantly increased the proportion of G0/G1 cells at 6 h post irradiation, but by 24 h post irradiation, the proportion of G0/G1 cells were significantly reduced in cells treated with metformin and 1.8 Gy, when compared to irradiated vehicle control ( Figure 2C )

Participates in the synthesis of acetylcholine, a key neurotransmitter that can enhance communication between nerve cells, which is crucial for mental performance and focus

Rodent models of nonalcoholic fatty liver disease

As we get older, our natural production of glutathione declines and our stores become depleted