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Spatial transcriptomics combined with single-cell RNA sequencing identified high expression levels of ferroptosis-related genes, including TFRC, NCO4, and SLC3A2, in granulosa cells of patients with ovarian senescence, while GPX4 expression was notably low (Lin et al., 2023)

doi: 10.1007/s10815-009-9341-7 33 GeMMGaoYYWuBBYanKQinQWangHet al

Homocysteine metabolism in renal failure

We assessed the risk of a composite kidney outcome, including confirmed 40% eGFR loss or end-stage kidney disease, and the risk of new macroalbuminuria

When activated, GLP-1R slows gastric emptying, reduces glucagon secretion, reduces appetite through central mechanisms, and reduces cardiovascular risk through pathways that are still being elucidated