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Patients who experience significant side effects at any dose can remain at that dose longer (6-8 weeks) before escalating, or step back to the previous dose temporarily before attempting escalation again
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Additionally, some studies suggest that GLP-1 receptor agonists might have a direct effect on kidney function, helping to increase uric acid excretion
The most well-known example of this in GLP-1r signaling was the failure of Taspoglutide in clinical trials
Our domestic facilities use research-grade standards throughout synthesis and purification
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