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Finally, after 48 h exposure to 1 mM MT, we quantified the proliferation marker PCNA using Western blot analysis

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Recent research further demonstrates that CAT suppresses Hypoxia-inducible factor-2 alpha (HIF-1) expression via activation of solute carrier family 2 member 1 (SLC2A1), effectively reducing ferroptosis-dependent chondrocyte damage and mitigating OA progression (Guan et al., 2023)