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Chronic treatment with PARP inhibitors increased NAD + levels and mitochondrial respiration in 10-week-old mice and triggered UPR mt and increased mitochondrial respiration and lifespan in worms 109,257

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This work was supported by grants from the Deutsche Forschungsgemeinschaft to BG (GR 936/171 and 17-2) and by the Collaborative Research Center SFB1078 (Humboldt Universitt zu Berlin, TP A5 to RH)

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