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Neurology 89 , 21572166 (2017)

Clinical trials of semaglutide 2.4 mg (Wegovy) showed an average weight reduction of around 15% of body weight over ~68 weeks

Insulin, androgens, and estrogens tend to enhance IGF-1 secretion, whereas glucocorticoids inhibit it

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Rarely, other causes of fatty liver can lead to cirrhosis, including: Long-term treatment with steroids, certain anti-HIV drugs, and other medications A health condition youre born with, like Wilson disease Whatever the cause of your fatty liver, you can also take steps to prevent progression to cirrhosis