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The next, phase 1b clinical trial in adults with T2DM compared once weekly retatrutide (0.5, 1.5, 3, 3 mg starting dose increased to 6, 3 mg starting dose increased to 12 mg) versus placebo versus dulaglutide 1.5 mg over 12 weeks [63]

IQVIA blog, October 2024: Wang et al, Associations of semaglutide with first-time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real-world data in the US

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Hepatitis B is a contagious liver disease with infection levels ranging from mild illness to serious lifelong infection that can lead to liver failure, liver cancer or cirrhosis, which is permanent scarring of the liver

It functions as an agonist at the GLP-1, GIP, and glucagon receptors with activity across all three targets