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Statistical Design The study was designed to detect a difference of 0.5 standard deviation (SD) in the change (baseline to week 4) of average fatigue between the two arms, with 85% power, assuming an intrapatient correlation of 0.5, using a Wilcoxon-Mann-Whitney test with a two-sided type I error of 5%

Despite severe infection and relatively weak granulomas formation, these effects of NAC were also seen in cells from patients with Type 2 DM (68)

LEfSe results showed enrichment of beneficial Lactobacillus taxa and suppression of potential pathogens (e.g., Streptococcus, Pasteurellaceae, Terrisporobacter ) in controls

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