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The relevance of NAD + -boosting strategies for mitochondrial homeostasis and implications for health benefits in the context of aging and disease in preclinical and clinical studies will be discussed in the Preclinical and clinical applications of NAD + -modulating interventions for mitochondrial homeostasis and health benefits section

is published in the Journal of Clinical Endocrinology and Metabolism and is available through PubMed

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However, Sp-L-DOPA combination showed consistent negative geotaxis even during the wearing-off phase, representing substantial alleviation of L-DOPA toxicity and promotion of enhanced mitochondrial and cellular health in dopaminergic neurons