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JAMA Ophthalmol 134(12):13651372 Sharma N et al (2017) Comparison of oral Voriconazole versus oral Ketoconazole as an adjunct to topical Natamycin in severe fungal keratitis: a randomized controlled trial

But - clinical trials aren't substantial, it's still not approved for use (indicating more safety data is warranted), most work is pre-clinical and or done with rodents not humans and given its ability to upregulate human growth hormone and angiogenesis (create new blood vessels), someone with a history of cancer would be advised to take serious precautions

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The mild immune response may not have entirely knocked out the virus allowing the remaining viral particles to contribute to chronic symptoms

Nasseri, MD