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HOMA, Homeostatic Model Assessment

Anti inflammatory and antioxidant signaling Evidence sources : cell and animal work, narrative and mechanistic reviews Confidence : moderate on signaling changes Main caveats : shifts in biomarkers are not the same as demonstrated clinical benefit

Clinical studies have investigated ALA for oxidative stress, metabolic health, and diabetic neuropathy, making it one of the most versatile alternatives to NAC.65 66 67 Our guide to the best alpha-lipoic acid supplements takes a closer look at the evidence and our top recommendations

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