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In expanded populations, comparing semaglutide versus sitagliptin for the composite outcome of myocardial infarction or stroke yielded a hazard ratio of 0.82 (95% confidence interval (CI) 0.74 to 0.91), and comparing tirzepatide versus dulaglutide for the composite outcome including mortality yielded a hazard ratio of 0.87 (95% CI 0.75 to 1.01)

The most commonly reported side effects of GLP-1 medications are gastrointestinal symptoms like nausea, abdominal pain, and constipation

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Liu, L., Chen, J., Wang, L., Chen, C., & Chen, L

Levels of brain natriuretic peptide are associated with peripheral arterial disease in subjects with type-2 diabetes mellitus