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Science 342(6158):1243417. [doi.org]

A key pathway involves the activation of the FAK-paxillin signaling cascade

In addition, the combination of geniposide with VitE significantly reduces UCP2, NF-B and tumor necrosis factor- (TNF-) protein expression

PMID 33837819

The bonds that give them their structure and function are fragile in ways that most pharmaceuticals arent, as a 2025 review in Protein & Peptide Letters on therapeutic peptide stability documented: heat and environmental exposure during storage and transit break down amino acid bonds, degrading the compound before it reaches the consumer