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doi:10.1097/AJP.0b013e3181759231 [DOI] [PubMed] [Google Scholar] 45.Phillips TJ, Cherry CL, Cox S, Marshall SJ, Rice AS

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stopping: Instead of stopping abruptly, some providers may recommend gradually reducing the dose to help manage the return of hunger and support a smoother transition

In trials of the combination of GLP-1 and GIP agonists, patients lost an average of 25% of their initial body weight at the highest dose. GLP-1 medications, which are available by prescription only and administered by weekly injection, are approved for people with a body mass index above 30, or above 27 with a comorbidity, such as type 2 diabetes, prediabetes, high blood pressure or sleep apnea