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The closest human evidence in its drug class is Athira Pharma's fosgonimeton (ATH-1017), a structurally distinct molecule in the same HGF/c-Met program whose Phase 2/3 LIFT-AD Alzheimer's trial failed its primary endpoint in September 2024 (GST 0.08, P=.70)

These side effects typically resolve without the need for medical intervention

Wet AMD (neovascular): Abnormal blood vessel growth under retina leaking fluid and causing vision loss

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Example: Someone stable on levothyroxine for years, TSH around 2, starts an over-the-counter supplement with L-carnitine and notices increasing tiredness and a later TSH of 5