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To investigate the role of USCs in bladder remodelling, we isolated bladder USCs from convalescent mice (4 weeks after the initiation of antibiotics), from both those with self-resolved infection (resolved) and those that developed chronic infection (sensitized), as well as from age-matched nave mice as controls and established USC lines ( n = 4 per infection history) (Fig

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Maintenance (week 17 onward, 2.4 mg): the dose carried through the 68-week trial endpoint

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These non-invasive treatments are a powerful alternative to surgical procedures, offering an effective solution with minimal disruption to your daily life