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A neuroimaging study suggested that depression strongly leads to memory dysfunction given that morphological changes in the brain of depressed patients, such as atrophy and abnormal alteration of the frontal cortex, thalamus, and hippocampus, is related to cognitive impairment (Zhang et al., 2016)

The reaction conditions were 50 C for 2 min (1 cycle), 95 C for 20 s (1 cycle), 95 C for 3 s and 60 C for 30 s (40 cycles)

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