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Most chemicals, either produced by the body or to which we are exposed through our diet and environment, first undergo phase I detoxification, which produces highly reactive and carcinogenic by-products

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Sedating Antihistamines (Diphenhydramine/Doxylamine) Mechanism: Antihistamines block H1 receptors, causing drowsiness

The nonenzymatic antioxidants ascorbate (AsA) and glutathione (GSH), their respective oxidized formsdehydroascorbate (DHA) and glutathione disulphide (GSSG) and the enzymes that continuously recycle them constitute the major ROS scavenging system in plantsthe ascorbateglutathione cycle

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