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One hour after refeeding, blood samples were collected via cheek bleeds or cardiac puncture, and plasma was isolated and snap-frozen for subsequent hormone analysis by ELISA
Unlike full-length growth hormone, AOD-9604 does not upregulate IGF-1, does not induce insulin resistance in reported toxicology models, and does not measurably affect linear growth in adult animal models
Used together, they amplify both the magnitude and frequency of growth hormone pulses without increasing cortisol or prolactin
Generally speaking, the absorption efficiency after oral administration may be affected by the gastrointestinal environment, and different physiological states of the gastrointestinal tract may lead to differences in absorption rate and degree
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