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Interaction of the programmed cell death 1 molecule (PD-1) expressed by T cells with its ligands PD-L1 and PD-L2, which are expressed by isolated hBECs, was shown to be a key factor in migration (Pittet et al., 2011), whereas PECAM-1 was not crucial (Wimmer et al., 2019)
In future work, further studies on LALPVYN are still needed, with the aim of clarifying whether LALPVYN also possesses the same antioxidant activity in mice as in previous studies