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Despite rapid progress in this field, there remains a lack of systematic integration regarding how key metabolic axes, including arginine metabolism, tryptophan catabolism, and glutamine metabolism, coordinately or antagonistically drive macrophage functional reprogramming, as well as the conservation, heterogeneity, and translational significance of these changes across different autoimmune-related diseases

Patients should be monitored closely for any signs of respiratory distress

Use in humans Niacin is a long-known vitamin referred to as vitamin B3 or PP (pellagra preventive)

doi: 10.1210/er.2011-1034