Without human trial data, clinicians and patients are making decisions based on incomplete information, and the self-reported adverse effect profile anxiety, palpitations, insomnia, fatigue is not benign enough to ignore
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Progress photos in consistent lighting and posture, taken every 2-4 weeks, reveal changes that gradual daily observation misses
IV administration might be chosen if you are already on IV fluids or need a very rapid correction of vitamin levels
They evidenced no superiority of one infiltrative method over the others, reporting only increased pain in the immediate post-infiltration period, most likely, according to the authors, induced by the leukocyte-mediated response in the group of patients receiving LR-PRP