glp 1 drugs in development GLP-1 Medications for Weight Loss: Semaglutide vs Tirzepatide vs Retat – Revolution Health & Wellness GLP-1 Market Industry Trends and

Li, Yiwei, and Fazlul H

About 10% of tirzepatide participants had a heart-rate increase above 20 bpm during escalation, compared with 3% on placebo. A lean Japanese cohort reached +10 to +13 bpm, and 23% of Japanese participants at 15 mg crossed the abnormal-pulse threshold versus 7% of other participants, despite only 17% higher exposure. Lean and East Asian bodies showed greater cardiovascular sensitivity than exposure alone predicted

10.3390/ijms22094888 150 MengL.JanS

Research has shown Silymarin from Milk Thistle to be 'immuno-modulatory' and anti-inflammatory, and may be of use to those who have autoimmune conditions and inflammatory diseases

Free Radic Biol Med 22:885888