Handelman however cautions that evidence for effectiveness of carnitine supplements in dialysis suffers from trials limited in subject number and open labeled, and suggests more rigorous testing is needed [55]
During viral infection, the antioxidant defense of the host is perturbed, resulting in oxidative stress 48
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Unresolved safety questions The staff review identified uncertainty about immunogenicity, aggregation, peptide-related impurities, hypersensitivity, route-specific risk, repeated exposure, and long-term use