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DILI often mimics acute viral liver infections and lacks skin symptoms, making diagnosis challenging

Epigenetic characteristics associate with disease history Our data indicate that a previous infection results in USC-intrinsic changes that are heritable over many generations of cell culture

This pro-inflammatory microenvironment niche not only impacts the functionality of immune cells but also influences the differentiation of myeloid immune cells, thereby amplifying the reduced ability to effectively clear senescent cells of senescent macrophages, promoted calcification of VSMCs

Numerous preclinical studies have also suggested that tocotrienols might be beneficial in the prevention of chronic diseases (12)

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