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43 Nuclear transcription factor-B (NF-B) Inflammatory pathway signaling plays a key role in regulating the amount of ROS in the cell

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Similarly, TMAO increased the mRNA expression of the stress-induced heat shock proteins HSP60 and GRP78, a hallmark of endoplasmic reticulum stress induction, which was related to an increased risk of AS (Mohammadi et al., 2015)