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On the contrary, potential harmful effects were suggested [8] one of the possible mechanisms includes increased heart rate associated with liraglutide use [31]

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List of GLP-1 ini6al approvals since 2005 *products no longer on the market Notable GLP-1 Agonists for Obesity The first GLP-1 drug approved for obesity was Saxenda (liraglutide) from Novo Nordisk, a twice-daily injectable that demonstrated a 7% weight reduction over a year upon its approval

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however, many patients retain 5070% of their weight loss through sustained habit change and continued exercise