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A useful approach is to take a control biopsy from the contralateral side of the face.11 In general, biopsy of suspicious or changing pigmented lesions on the face is recommended.12 Excisional biopsy is the most accurate diagnostic method in LM, but because lesions are often large and located in cosmetically sensitive areas, punch biopsy is the most widely used procedure,13 despite the problem of sampling error.14 Based on observational studies by Stevens and Cocherell,15 deep incisional biopsy extending as far as the subcutaneous tissue with a punch of at least 5mm can minimize this source of error
F2-IsoPs deserve special attention because serum F2-IsoPs levels were higher in asthma patients than in healthy subjects, and were also correlated with disease progression (85)
The error has been corrected in the print, PDF and HTML versions of this article
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Third-party COAs from independent laboratories are more reliable
