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The GLP-1 market boom, fueled by celebrity endorsements and supply shortages, has telehealth companies like Medvi capitalizing on demand
The increased glutaminolysis can be achieved in fibroblasts by upregulation of the rate-limiting enzyme glutaminase 1 (GLS1) (224) and TGF- (223)
however, the average BMI plateaued in 2022 and declined in 2023 (Rader et al., 2024)
This leads to a faster breakdown of glutathione (GSH), a key antioxidant