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J Appl Genet 57:107112 Baumann A, Kiener MS, Haigh B, Perreten V, Summerfield A (2017) Differential ability of bovine antimicrobial Cathelicidins to mediate nucleic acid sensing by epithelial cells

A history of gallstones, gallbladder disease, pancreatitis, rapid weight loss, or a family history of gallstones should be discussed with the prescribing clinician

In clinical practice, she explained, physicians start low and raise the dose gradually in a process called titration, an approach that "balances treatment efficacy with side effects." Sometimes they intentionally keep someone at a lower, submaximal dose rather than pushing to the maximum