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The decrease in antioxidant system capacity weakens the antioxidant defense of ARDS patients and makes them more susceptible to oxidative stress damage

Low dead space syringes Low dead space (LDS) syringes are engineered to minimize the volume trapped after injection

Contraindications include pregnancy, active cancer, and severe liver or kidney disease

41 Type 1 was the dominant genotype, present in 74% of patients, almost evenly divided between subtypes 1a and 1b

Development of the Predictive Model The predictive model for the SOUL trial was developed using the pooled HR estimate along with the preadjudicated assumptions mentioned in the trial protocol