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Expansion into Chronic Weight Management: November 2023 While many people used tirzepatide off-label for weight loss throughout 2022 and early 2023, the next major milestone occurred in late 2023

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HbA 1c was reduced in SURPASS 15, using from 5 to 15 mg of TZP per week, by between 1.69 to 2.58%, and a new plateau of HbA 1c and fasting serum glucose (FSG) was reached with approximately 2430 weeks of treatment