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Clinical trial data from Eli Lillys Phase 2 study showed that the 12mg weekly dose produced an average weight loss of 24.2% over 48 weeks, with over 80% of participants losing at least 15% of their starting body weight

In real-world trials, fewer than 10% of patients discontinued both oral and injectable semaglutide due to side effects

If you must change vendors during a protocol, treat the new source as unverified

In fact, these side effects are largely why its standard practice for clinicians and pharmaceutical companies alike to recommend a dosing schedule that gradually brings patients up to their maintenance dose

& Krawetz, R